RM CARVEDILOL 6.25MG FC TAB SOLD PER PIECE

For the treatment of:

• Hypertension
• Chronic stable angina pectoris
• Adjunctive treatment of moderate to severe stable chronic heart failure

 How much and how often should you use this medicine?

The tablets should be taken with adequate supply of fluid. The tablets do not need to be taken with a meal.  However, it is recommended that heart failure patients take their Carvedilol medication with food to allow the absorption to be slower and the risk of orthostatic hypotension to be reduced.

Essential Hypertension

• Adults: The recommended initial dose is 12.5 mg once a day for the first two days. The treatment is continued at the dose 25 mg  per day.
• Elderly:  The recommended initial dose in hypertension is 12.5 mg once a day.

Chronic Stable Angina Pectoris

• Adults: The recommended initial dose is 12.5 mg once a day for the first two days. Thereafter, the treatment is continued at the dose 25 mg per day.
• Elderly: The recommended initial dose is 12.5 mg twice daily for two days. Thereafter, the treatment is continued at the dose 25 mg twice daily, which is the recommended maximum daily dose.

Children and adolescents below 18 years of age:

 There is insufficient data of the efficacy and safety of Carvedilol.

Contraindications

• Digoxin: increased risk of digoxin toxicity
• Insulin and oral antidiabetic drugs: increased risk of severely low blood sugar levels
• Clonidine: severe decrease in blood pressure and heart rate
• Verapamil, Diltiazem